Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/316103507?client_source=feed&format=rss
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Sunday, June 30, 2013
Saturday, June 29, 2013
Divorce early in childhood affects parental relationships in adulthood
June 29, 2013 ? Divorce has a bigger impact on child-parent relationships if it occurs in the first few years of the child's life, according to new research. Those who experience parental divorce early in their childhood tend to have more insecure relationships with their parents as adults than those who experience divorce later, researchers say.
"By studying variation in parental divorce, we are hoping to learn more about how early experiences predict the quality of people's close relationships later in life," says R. Chris Fraley of the University of Illinois at Urbana-Champaign. Psychologists are especially interested in childhood experiences, as their impact can extend into adulthood, but studying such early experiences is challenging, as people's memories of particular events vary widely. Parental divorce is a good event to study, he says, as people can accurately report if and when their parents divorced, even if they do not have perfect recollection of the details.
In two studies published today in Personality and Social Psychology Bulletin, Fraley and graduate student Marie Heffernan examined the timing and effects of divorce on both parental and romantic relationships, as well as differences in how divorce affects relationships with mothers versus fathers. In the first study, they analyzed data from 7,735 people who participated in a survey about personality and close relationships through yourpersonality.net. More than one-third of the survey participants' parents divorced and the average age of divorce was about 9 years old.
The researchers found that individuals from divorced families were less likely to view their current relationships with their parents as secure. And people who experienced parental divorce between birth and 3 to 5 years of age were more insecure in their current relationships with their parents compared to those whose parents divorced later in childhood.
"A person who has a secure relationship with a parent is more likely than someone who is insecure to feel that they can trust the parent," Fraley says. "Such a person is more comfortable depending on the parent and is confident that the parent will be psychologically available when needed."
Although there was a tendency for people to experience more anxiety about romantic relationships if they were from divorced families, the link between parental divorce and insecurity in romantic relationships was relatively weak. This finding was important, the researchers say, as it shows that divorce does not have a blanket effect on all close relationships in adulthood but rather is selective -- affecting some relationships more than others. They also found that parental divorce tends to predict greater insecurity in people's relationships with their fathers than with their mothers.
To help explain why divorce influences maternal relationships more than paternal ones, and to replicate the first study's findings, Fraley and Heffernan repeated their analysis with a new set of 7,500 survey participants. Unlike in the first study, however, they asked the participants to indicate which of their parents had been awarded primary custody following their divorce. The researchers speculated that paternal relationships were more insecure following divorce because mothers are more likely than fathers to be awarded custody.
The majority of participants -- 74 percent -- indicated that they had lived with their mothers following divorce or separation, while 11 percent indicated living with their fathers; the remainder lived with grandparents or other caretakers. The researchers found that people were more likely to have an insecure relationship with their father if they lived with their mother and, conversely, were less likely to have an insecure relationship with their father if they lived with him. The results were similar with respect to mothers.
While it is premature to speculate on the implications of this work for decision-making regarding child custody, the work is valuable as it suggests that "something as basic as the amount of time that one spends with a parent or one's living arrangements" can shape the quality of child-parent relationships, write Fraley and Heffernan.
"People's relationships with their parents and romantic partners play important roles in their lives," Fraley says. "This research brings us one step closer to understanding why it is that some people have relatively secure relationships with close others whereas others have more difficulty opening up to and depending on important people in their lives."
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/yQxmCO4tAxw/130629164737.htm
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Sluggish April GDP confirms Canadian economy is slowing
By David Ljunggren
OTTAWA (Reuters) - Canada's economy grew by just 0.1 percent in April from March, Statistics Canada said on Friday, confirming that after a strong first quarter, growth is slowing amid continuing global economic uncertainty.
Although April marked the fourth consecutive month-on-month gain, it was the smallest of the four increases. The figure matched analysts' expectations.
"(This) is no big surprise and fully consistent with the slow-motion expansion Canada now finds itself in. The modest April gain almost precisely matches the average increase seen over the past year," BMO Capital Markets chief economist Doug Porter said in a note to clients.
The Bank of Canada forecasts that second-quarter growth on an annualized basis will be 1.8 percent, down from the 2.5 percent in the first quarter.
The output of service industries expanded by 0.3 percent in April. Goods production fell by 0.3 percent on a decline in mining, quarrying and oil and gas extraction.
Porter and other analysts said second-quarter growth would be also hurt by major floods that hit Canada's oil capital last week, as well as a construction strike in the province of Quebec.
The Canadian dollar briefly pared its losses following the release of the data, before weakening back to C$1.0500, or 95.23 U.S. cents. It finished Thursday's North American session at C$1.0475 versus the U.S. dollar, or 95.47 U.S. cents.
The report showed wholesale and retail trade advanced by 0.6 percent and 0.5 percent, respectively, while the finance and insurance sector grew by 0.6 percent.
Manufacturing grew by 0.2 percent with durable goods output up by 0.5 percent on gains in computer and electronic products. Non-durable goods production dropped by 0.3 percent on declines in petroleum and coal products.
"The domestic economy is likely to remain subdued, which will prevent headline growth from moving materially above its trend rate," said TD Securities chief Canada macro strategist David Tulk.
Canada relies heavily on the economy of the United States, where the most recent data on consumer spending and jobs data suggests lukewarm growth.
Separately, Statscan said producer prices were unchanged in May from April as higher prices for petroleum and coal products offset declines in primary metal product and lumber prices. Analysts had estimated a 0.1 percent increase.
Petroleum and coal products climbed by 1.1 percent after two consecutive declines, pushed higher by a 3.6 percent increase in the price of gasoline.
Primary metal products slipped by 1.1 percent in part due to lower prices for gold, gold alloys, silver and platinum. Raw materials prices rose by 0.2 percent.
(With additional reporting by Andrea Hopkins in Toronto; Editing by Jeffrey Hodgson and Steve Orlofsky)
Source: http://news.yahoo.com/canadian-economy-grew-0-1-percent-april-services-124841741.html
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Rodzilla on the rampage: Inside the sports-entertainment career of Dennis Rodman
On the night of June 8, 1998, Michael Jordan and his Chicago Bulls were in the middle of a grueling practice session in the United Center, running drills after their loss to the Utah Jazz in the first game of the NBA Finals. Dennis Rodman ? the team?s problematic, but effective starting forward ? was some 300 miles away in Auburn Hills, Mich., beating a man with a steel chair.
Less than two weeks away from winning his fifth NBA championship ring, Rodman had opted to blow off practice in favor of appearing on WCW?s Monday Nitro ? then the most-watched program on cable television. ?The Worm? was scheduled to team with ?Hollywood? Hulk Hogan against Diamond Dallas Page and Utah Jazz forward Karl Malone at July 2?s Bash at the Beach pay-per-view. He had to get his licks in when he could.
Watch Rodman in tag team action at Bash at the Beach '98
?They whipped the [hell] out of me with those chairs,? Page told WWEClassics.com. ?But, that night, the highlight of [?SportsCenter?] was what? Dennis Rodman no-shows practice and ends up on Nitro. That was huge.?
The Chicago Bulls organization fined Rodman $10,000 for his actions, but it hardly mattered. For the first time in his career, the famously difficult Rodman was being embraced by an industry that could appreciate a 6-foot-7 dude with hair like a scoop of rainbow sherbet. Not only was Rodzilla being encouraged to play up the flamboyance and arrogance that made him the NBA?s problem child ? he was being rewarded for it.
?The scuttlebutt was he got $1.2 million for the three matches he signed for,? former WCW producer Kevin Sullivan said.
Rodman had made his entry into professional wrestling a year before he skipped practice, pledging his allegiance to The Hulkster?s New World Order in a prerecorded segment on the March 10, 1997, edition of Nitro. It had already been a banner year for The Worm?s growing cult of personality. In those first months alone, he released his second autobiography (complete with a cover photo of him nude and painted like a tiger), co-starred with Jean Claude Van Damme in the action movie ?Double Team? and kicked a courtside cameraman in the crotch, resulting in a $25,000 fine and an 11-game suspension.
Witness Rodman joining the nWo
It was all part of the ?bad as I wanna be? ethos Rodman had been pushing since he came out of his shell during a 1993 run with the San Antonio Spurs. Before that revolutionary year, Rodman had been a janitor-turned-defensive marvel for the hardscrabble Detroit Pistons of the late ?80s and early ?90s. His preternatural rebounding abilities earned him respect, but when he hit the court in Texas with platinum hair, a nose ring and tattoos ? long before inked sleeves were requisite in the league ? he became the NBA?s most recognizable player next to Michael Jordan.
View CommentsSource: http://www.wwe.com/classics/wcw/dennis-rodman-in-wcw
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'Heat' broadens buddy-cop movie mix with 2 women
LOS ANGELES (AP) ? The buddy-cop movie has been around for decades, typically starring two mismatched male characters, except for those few instances where the buddies are actually a man and a dog, as in 1989's "K-9" and "Turner & Hooch."
Now Sandra Bullock and Melissa McCarthy are getting into the mix with "The Heat," and advance ticket sales show fans are warming quickly to the concept.
Movie website Fandango says "The Heat," from 20th Century Fox, is the most popular offering this weekend, comprising 35 percent of nationwide ticket sales.
"It's taking a genre that very much appeals to one demographic, and inserting stars who appeal to another demographic," which makes the film equally appealing to men and women, said Dave Karger, chief correspondent for Fandango. "It has the action and it has the comedy which the guys are probably going to go for, then the female-friendship angle, too. Women just love Sandra Bullock and Melissa McCarthy and are excited to see a big summer movie with two women in the lead."
The standard buddy-cop formula is at play here, with Bullock playing an uptight, lonely FBI agent who's paired with McCarthy's foul-mouthed, no-nonsense Boston police officer to take down a drug dealer. But having women play the incompatible cops makes the film unusual, if not downright groundbreaking. (The 1988 movie "Feds" focused on the comedy of two women accepted to the FBI training academy.)
"As insane as it sounds, it's such a unique thing to have two women," Karger said. "They thought of putting a dog in there before they thought of putting a woman in there, but that's Hollywood for you."
It's not only unusual to see two women take on the buddy-cop genre, but two women over 40 opening a big summer picture, said Tatiana Siegel, who covers the film industry for the trade publication The Hollywood Reporter.
"You might see two women in a movie like a Sundance movie, but this is a major, heavily marketed summer movie with franchise potential that in the past would have featured two men starring in it," Siegel said.
But she adds that the film is no great risk for Fox because of its relatively modest budget and the star-power of McCarthy and Bullock.
Karger said "Bridesmaids" cleared the way for this film: "Clearly the massive success of 'Bridesmaids' allowed a movie like this to exist."
"The Heat" is directed by "Bridesmaids" director Paul Feig, who declined to be interviewed for this story.
Box-office analyst Paul Dergarabedian predicts that "The Heat" could beat its buddy-action competitor, "White House Down," also opening Friday, which stars Channing Tatum and Jamie Foxx.
If "The Heat" wins the box-office race, it would be "a huge coup" for actresses, Siegel said.
"Actresses in general are paid less than their male counterparts," she said. "If this movie finishes first, it speaks volumes about the work of two actresses and how audiences are more than willing to support movies like this."
___
AP Entertainment Writer Sandy Cohen is on Twitter: www.twitter.com/APSandy .
___
Online:
http://www.theheatmovie.com/
Source: http://news.yahoo.com/heat-broadens-buddy-cop-movie-mix-2-women-183836107.html
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Sound and nonsense
To a nonnative speaker, what a difference a misheard word makes.
Baltimore Oriole ? in Indiana
Bob Wellinski/The LaPorte Herald-Argus/AP
EnlargeI used to dream of a stadium filled with fans, everyone on their feet and holding a chocolate sandwich cookie, chanting, "Oreos, Oreos, Oreos," as Baltimore's baseball team won the World Series.
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I should be clear that (a) I know nothing about baseball, (b) I love Oreos, and (c) English is my second language. It is incredibly easy for me to mix up words that sound similar.
My Oreos dreams persisted until one night when I was having dinner with my friend Dave, a sports fanatic, and the subject of baseball came up.
"How cool is that?" I said. "A baseball team is named after a cookie!"
"What team is named after a cookie?" Dave asked.
"Oreos ? you know, the Baltimore team."
Dave cast a long, silent glance at me and then said: "The Orioles are named after a bird, not a cookie." He proceeded to spell it, trying to get me to pick up the difference between orioles and Oreos. I could hear the laughter in his voice.
This business of mixing up words is embarrassing, especially when I mispronounce people's names. Craig and Greg; John and Joan; Marian and Myriam. A few years ago, I worked with a Gail, who sat across from me, and a Gil, who sat next to me. When I called out to Gail (or to Gil), nine times out of 10, both would reply, "Are you talking to me?"
My son Alex laughed his pants off (not pans or pens, but pants) when I told him I had a "sneaker" for a snack. "Mom," he said, "Snickers, S-n-i-c-k-e-r-s, is a candy bar. Sneaker, s-n-e-a-k-e-r, is the shoe."
At least I am not swimming alone in this sea of mispronunciation. According to englishforums.com and collegenet.com, both native and nonnative speakers have trouble pronouncing words like nuclear, Realtor, jewelry, library, and rural. Nuclear is often mispronounced "nu-cu-lear," Realtor becomes "Rea-la-tor," and jewelry changes to "jew-le-ry." Dr. Language at yourdictionary.com lists the 100 most often mispronounced words and phrases in English. For all intents and purposes (not "all intensive purposes"), here are some words to watch out for.
?Carpal tunnel syndrome is a medical condition, not an instance of carpooling in a tunnel.
?While a card shark sounds more dangerous, the word is cardsharp.
?Bob wire did not fence off the American frontier, barbed wire did.
?A blessing in the skies may refer to a rainbow, but you probably misheard "a blessing in disguise."
"Take your time speaking, correctly enunciating each word," is Dr. Language's advice.
An added bonus is that pronouncing words correctly helps you spell them accurately, too, says Dr. Language. A friend of mine, who is a Venezuelan living in the United States, once wrote "see me before you live" on a note to one of his staff. Had my friend pronounced "live" and "leave" properly, he could have avoided ever having to employ a dead person.
"Pay particular attention to new sounds," says Linda Miller, associate director at the Emerson College Writing Center, who has taught English as a second language for 30-plus years. Many English sounds don't exist in other languages, so nonnative speakers like me often substitute unfamiliar sounds with sounds they know from their own language. Linda was sometimes called "Rinda" because the "l" sound doesn't exist in the speaker's native language. And I had once announced my intention to memorize a "ple-teho-la" of English vocabularies in an ESL class. Chinese, my mother tongue, does not possess the sound of "th" or "r," after all.
Armed with tips from the experts, I asked Alex to demonstrate the correct pronunciation of orioles and Oreos. Unlike Eliza in "My Fair Lady" who was able to enunciate "rain," "Spain," and "plain" with clarity after some training, I never arrived at the epiphany of correctly distinguishing orioles from Oreos. Granted, Alex is no Professor Higgins and a two-minute lesson is all we could handle as mother and son.
I no longer dream about a stadium full of fans chanting "Oreos, Oreos." I now dream about a flock of little bright orange birds singing to me like a church choir with a mission: "Orioles, orioles, orioles...."
Source: http://rss.csmonitor.com/~r/feeds/csm/~3/qRQrdiOgcNg/Sound-and-nonsense
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Friday, June 28, 2013
Potential boost for world's food supply: Resistance gene found against Ug99 wheat stem rust pathogen
June 27, 2013 ? The world's food supply got a little more plentiful thanks to a scientific breakthrough.
Eduard Akhunov, associate professor of plant pathology at Kansas State University, and his colleague, Jorge Dubcovsky from the University of California-Davis, led a research project that identified a gene that gives wheat plants resistance to one of the most deadly races of the wheat stem rust pathogen -- called Ug99 -- that was first discovered in Uganda in 1999. The discovery may help scientists develop new wheat varieties and strategies that protect the world's food crops against the wheat stem rust pathogen that is spreading from Africa to the breadbaskets of Asia and can cause significant crop losses.
Other Kansas State University researchers include Harold Trick, professor of plant pathology; Andres Salcedo, doctoral candidate in genetics from Mexico; and Cyrille Saintenac, a postdoctoral research associate currently working at the Institut National de la Recherche Agronomique in France. The project was funded by the U.S. Department of Agriculture and Borlaug Global Rust Initiative.
The team's study, "Identification of Wheat Gene Sr35 that Confers Resistance to Ug99 Stem Rust Race Group," appears in the journal Science.
It identifies the stem rust resistance gene named Sr35, and appears alongside a study from an Australian group that identifies another effective resistance gene called Sr33.
"This gene, Sr35, functions as a key component of plants' immune system," Akhunov said. "It recognizes the invading pathogen and triggers a response in the plant to fight the disease."
Wheat stem rust is caused by a fungal pathogen. According to Akhunov, since the 1950s wheat breeders have been able to develop wheat varieties that are largely resistant to this pathogen. However, the emergence of strain Ug99 in Uganda in 1999 devastated crops and has spread to Kenya, Ethiopia, Sudan and Yemen, though has yet to reach the U.S.
"Until that point, wheat breeders had two or three genes that were so efficient against stem rust for decades that this disease wasn't the biggest concern," Akhunov said. "However, the discovery of the Ug99 race of pathogen showed that changes in the virulence of existing pathogen races can become a huge problem."
As a first line of defense, wheat breeders and researchers began looking for resistance genes among those that had already been discovered in the existing germplasm repositories, he said.
"The Sr35 gene was one of those genes that was discovered in einkorn wheat grown in Turkey," Akhunov said. "Until now, however, we did not know what kind of gene confers resistance to Ug99 in this wheat accession."
To identify the resistance gene Sr35, the team turned to einkorn wheat that is known to be resistant to the Ug99 fungal strain. Einkorn wheat has limited economic value and is cultivated in small areas of the Mediterranean region. It has been replaced by higher yielding pasta and bread wheat varieties.
Researchers spent nearly four years trying to identify the location of the Sr35 gene in the wheat genome, which contains nearly two times more genetic information than the human genome.
Once the researchers narrowed the list of candidate genes, they used two complimentary approaches to find the Sr35 gene. First, they chemically mutagenized the resistant accession of wheat to identify plants that become susceptible to the stem rust pathogen.
"It was a matter of knocking out each candidate gene until we found the one that made a plant susceptible," Akhunov said. "It was a tedious process and took a lot of time, but it was worth the effort."
Next, researchers isolated the candidate gene and used biotechnical approaches to develop transgenic plants that carried the Sr35 gene and showed resistance to the Ug99 race of stem rust.
Now that the resistance gene has been found, Akhunov and colleagues are looking at what proteins are transferred by the fungus into the wheat plants and recognized by the protein encoded by the Sr35 gene. This will help researchers to better understand the molecular mechanisms behind infection and develop new approaches for controlling this devastating pathogen.
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Thursday, June 27, 2013
Sharp to form LCD tie-up with China Electronics, license technology
By Mari Saito
TOKYO (Reuters) - Japan's Sharp Corp, a leading supplier of displays to Apple Inc, said Thursday it will form a $2.9 billion alliance with state-owned China Electronics Corp that includes an agreement by Sharp to license its advanced power-saving IGZO screen technology.
The new venture will be 92 percent owned by China Electronics, also known as CEC, which supplies equipment to China's military. The venture will set up a an LCD plant with the goal of mass-producing panel displays for televisions, notebook PCs and tablets in 2015.
Licensing IGZO, or indium gallium zinc oxide displays, fits into a strategy by cash-strapped Sharp to leverage its technology to bolster its finances. Sharp, in December, signed a pact with Qualcomm Inc, selling the U.S. company an equity stake for $120 million and agreeing to develop new screens based on IGZO technology.
IGZO screens boast power consumption as low as a tenth of conventional LCDs, high resolutions and faster reaction speeds. While an agreement to license the technology to a Chinese military-linked state company may raise eyebrows, Sharp does not exclusively own the technology, only being the first to commercialize it.
The agreement, which is a revised version of one agreed to with CEC in 2009, may instead represent a retreat by the Chinese company to win access to Sharp's more advanced tenth-generation LCD manufacturing techniques. CEC is planning to build an 8.5 generation facility.
Sharp is the only panel maker in the world to have built a tenth generation factory able to fabricate liquid crystal sandwiched in glass sheets thinner than a credit card that are 3.13 meters long by 2.88 meters wide. Smaller 8.5 generation sheets measure 2.2 meters by 2.5 meters.
CEC in November blamed deteriorating ties between Japan and China over their territorial spat in the East China Sea for shelving cooperation with Sharp to build a tenth-generation facility. Sharp, which sold a stake in its advanced LCD plant to Taiwan's Hon Hai Precision Industry last year, says no such agreement ever existed.
Thursday's deal, including the construction of the 8.5 generation factory in Nanjing, represents one of the highest-profile transactions between a Chinese and Japanese company since tensions flared last year over a chain of disputed islands known as the Senkakus in Japan and the Diaoyu in China.
A Sharp spokesman declined to say how much in royalties the company expected to receive for the technology transfer. A portion of those proceeds will be used to fund Sharp's 8 percent stake in the joint venture, the spokesman said.
The new joint-venture will represent a total investment of $2.9 billion for Sharp, which was rescued in October by its banks. To rebuild its business, Sharp has also sought closer ties to Samsung Electronics, selling it a 3 percent stake for $103 million and pledging to supply it with small display screens.
(Additional reporting by Sophie Knight; Writing by Tim Kelly; Editing by Matt Driskill)
Source: http://news.yahoo.com/sharp-form-lcd-tie-china-electronics-license-technology-082534336.html
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Iran urges Qatar's new emir to revise Syria policy
DUBAI (Reuters) - Iranian Foreign Minister Ali Akbar Salehi on Wednesday urged Qatar's new Emir Sheikh Tamim bin Hamad al-Thani to revise his country's policy of backing Syrian rebel groups.
"Hopefully Sheikh Tamim will contemplate the Syrian issue and regarding past policies, he will make a serious revision so we will be able to ... join hands and tackle the Syrian crisis," Salehi told a news conference in Tehran, broadcast by Press TV.
"Given this power transfer that has happened in Qatar, we are hopeful that Qatar will enter a new era in its international interactions both with regional countries and others," he said.
Shi'ite Iran has steadfastly supported Syrian President Bashar al-Assad and his forces since the beginning of the crisis in 2011. It accuses Sunni Gulf states Qatar and Saudi Arabia of arming what Assad describes as "terrorist" groups.
Iran says the removal of Assad would lead to a dangerous power vacuum and that any solution for Syria should be made by the people themselves and not imposed from the outside.
But backers of opposition rebels accuse Iran of hypocrisy, saying it has provided billions of dollars of financial and military support for Assad.
(Reporting by Marcus George; Editing by Jon Hemming and Janet Lawrence)
Source: http://news.yahoo.com/iran-urges-qatars-emir-revise-syria-policy-091038392.html
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Tuesday, June 25, 2013
Drinking Only Soda For 16 Years Linked To Woman's Heart Woes ...
A 31-year old woman's heart problems and fainting might have had
something to do with the fact that she drank only soda for about half
her life, according to a report of her case.
A blood test showed she had severely low potassium levels. And a test of her heart's electrical activity revealed she had a condition called long QT syndrome, which can cause erratic heart beats.
something to do with the fact that she drank only soda for about half
her life, according to a report of her case.
The woman, who lives in Monaco, a small country near southern France, was brought to a hospital after she fainted.
A blood test showed she had severely low potassium levels. And a test of her heart's electrical activity revealed she had a condition called long QT syndrome, which can cause erratic heart beats.
The woman did not have a family history of heart or hormone problems.
But she told her doctors that, since the age of 15, she had not drunk any water -- soda (specifically cola) was the only liquid she consumed. She drank about 2 liters (2 quarts) of cola daily, she said.
After abstaining from soda for just one week, the woman's potassium levels and heart electrical activity returned to normal.
Drinking too much cola may cause excess water to enter the bowels, which in turn leads to diarrhea, and loss of potassium, the researchers said.
High amounts of caffeine can also increase urine production and decrease potassium reabsorption, the researchers said. Potassium plays a role in helping a person's heartbeat, and low levels of potassium may cause heart rhythm problems.
After searching for other similar cases, the researchers found six reports of excessive cola consumption that were thought to be related to adverse medical problems, including heart rhythm problems.
"One of the take-home messages is that cardiologists need to be aware of the connection between cola consumption and potassium loss, and should ask patients found to have QT prolongation about beverage habits," said study researcher Dr. Naima Zarqane, of Princess Grace Hospital Centre in Monaco.
Future studies should examine whether those who drink cola excessively have lower potassium levels than people who don't drink cola, the researchers said.
Excessive soda consumption can also lead to weight gain, which is a risk factor for heart disease, the researchers said.
The case report was presented this week at the European Heart Rhythm Association meeting in Athens, Greece. It has not been published in a peer-reviewed journal.
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Source: http://planehealth.blogspot.com/2013/06/drinking-only-soda-for-16-years-linked.html
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Germany investigates commander of Nazi-led unit
BERLIN (AP) ? German prosecutors said Monday that they opened a formal preliminary investigation of a Minnesota man who was a commander of a Nazi-led unit during World War II, to determine whether there is enough evidence to bring charges and seek his extradition.
The Associated Press found that 94-year-old Michael Karkoc entered the U.S. in 1949 by lying to American authorities about his role in the SS-led Ukrainian Self Defense Legion, which is accused of torching villages and killing civilians in Poland. AP's evidence indicates that Karkoc was in the area of the massacres, although no records link him directly to atrocities.
Kurt Schrimm, the head of the special German prosecutors' office responsible for investigating Nazi-era crimes, said prosecutors "have opened a preliminary investigation procedure to examine the matter (and) seek documentation." It was unclear how long their examination might take.
Schrimm's office is responsible for determining whether there is enough evidence against alleged Nazi war criminals for state prosecutors to proceed with a full investigation and possible charges. The only charges that can be brought in such cases are murder and accessory to murder, as all other offenses fall under the statute of limitations under German law.
Germany has taken the position that people involved in Nazi crimes must be prosecuted, no matter how old or infirm, as it did in the case of retired Ohio autoworker John Demjanjuk, who died last year at age 91 while appealing his conviction as a guard at the Sobibor death camp.
Poland's National Remembrance Institute, which investigates Nazi and Soviet crimes, has said prosecutors are reviewing files on Karkoc's unit for any evidence that would justify charges and an extradition request.
It says the files were gathered during separate investigations into the killings of civilians in the village of Chlaniow, in southeastern Poland, and into Nazi suppression of the 1944 Warsaw Uprising against German occupation. The AP found documentation showing that Karkoc's unit was involved in both.
Karkoc's son, Andriy Karkos, has said that his father "was never a Nazi," and pointed to the portion of the AP story that said records don't show Karkoc had a direct hand in war crimes. He has said the family won't comment further until it has obtained its own documents and reviewed witnesses and sources.
A woman who answered the phone at Karkoc's Minneapolis home Monday refused to comment when a reporter from the Associated Press made contact.
__
Associated Press correspondent Doug Glass contributed to this report from Minneapolis.
Source: http://news.yahoo.com/germany-investigates-commander-nazi-led-unit-124902653.html
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Deal of the Day: Seidio SURFACE Case for Samsung Galaxy S4
The June 25 ShopAndroid.com Deal of the Day is the Seidio SURFACE Case for Samsung Galaxy S4. Crafted from a hard yet flexible material, the SURFACE Case provides an amazingly thin layer of protection without adding the excessive bulk of other cases. This case consists of interlocking top and bottom pieces that fit your Galaxy S4 snugly. Available in black, blue, red, purple, pink and white.
The Seidio SURFACE Case is available for just $19.00, 37% off today only. Grab yours while supplies last!
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Source: http://feedproxy.google.com/~r/androidcentral/~3/Ohia3mfU8L0/story01.htm
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Sunday, June 16, 2013
Medical researchers design variant of main painkiller receptor
June 14, 2013 ? Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their corresponding receptors, but access to meaningful quantities of these receptors that can work in experimental conditions has always been a limiting factor.
Now, an interdisciplinary collaboration between researchers at the University of Pennsylvania has developed a variant of the mu opioid receptor that has several advantages when it comes to experimentation. This variant can be grown in large quantities in bacteria and is also water-soluble, enabling experiments and applications that had previously been very challenging or impossible.
The study was led by Renyu Liu, an assistant professor in the Department of Anesthesiology and Critical Care at Penn's Perelman School of Medicine, and Jeffery Saven, an associate professor in the Department of Chemistry in the School of Arts and Sciences. Jose Manuel Perez-Aguilar, then a graduate student in the Department of Chemistry, and Jin Xi, Felipe Matsunaga and Xu Cui, lab members in the Department of Anesthesiology and Critical Care, along with Bernard Selling of Impact Biologicals Inc., contributed significantly to this study.
Their research was published in the Journal PLOS ONE.
The mu opioid receptor belongs to a class of cellular membrane proteins called G protein-coupled receptors, or GPCRs. Involved in wide range of biological processes, these receptors bind to molecules in the environment, initiating cellular signaling pathways. In the case of this receptor, binding to opioid molecules leads to a profound reduction of pain but also to a variety of unpleasant and potentially fatal side-effects, a problem that researchers from multiple disciplines are attempting to address.
"There are two directions for solving this problem in basic science, either working on the opioid molecule or working on the receptor," Liu said. "We're doing the latter."
Experimenting on the mu opioid receptor has been challenging for several reasons. The human receptor itself is relatively scarce, appearing in small quantities on only a few types of cells, making harvesting appreciable amounts impractical. Researchers have also been unable to grow it recombinantly -- genetically engineering bacteria to express the protein en masse -- as some parts of the protein are toxic to E. coli. Hydrophobic, or water-hating, amino acid groups on the exterior of the receptor that help it sit in the cell's membrane also make it insoluble in water when isolated.
The researchers set out to address these challenges by computationally designing variants of the mu opioid receptor. This task had challenges of its own; their research was conducted long before the crystal structure of receptor was known.
"The problem with this receptor is that the native structure has only very recently been solved and only a significant re-engineered mouse model at that," Liu said. "When we started this project, we were blind."
Starting with only the gene sequence for the human version of the receptor, the researchers knew the order of the protein's amino acids but not how they were folded together. The structures for other GPCRs, such as rhodopsin and the beta-2 adrenergic receptor, were known at the time, however.
"Based on the comparison of our sequence to the sequences of those GPCRs, we built a computer model of the protein," Saven said. "When the structure of the mouse version of this receptor appeared, we were able to compare our model to that structure, and they matched up really well."
From that comparison, the researchers were able to identify the hydrophobic amino acids on the exterior of the structure, as well as some of those that were potentially toxic to E. coli.
"The objective then was to redesign those exterior amino acids," Saven said. "Based on the physical and chemical interactions these amino acids have with each other and with water, we were able to identify sequence combinations that are consistent with the model -- where atoms don't overlap in space -- and preferentially occupy the exterior surface with ones that are water soluble."
Replacing 53 of the protein's 288 amino acids, the research team introduced the new gene sequence into E. coli, which were able to produce large quantities of the variant. Beyond looking like the now-available mouse mu opioid receptor, the researchers were able to show its value to future studies by performing functional tests.
"We showed that this water-soluble form of the protein can compete with the native, membrane-based form when binding with antagonists that are fluorescently labeled," Saven said. "You can watch the fluorescence shift as more of these water-soluble variants are floating around in the solution."
The team's computational approach enables further iterations of the variant to be more easily designed, meaning it can be tweaked alongside experimental conditions.
"This is a great product that can do a lot of things," Liu said. "You can use this variant to look at the structure-function relationship for the receptor, or even potentially use it as a screening tool."
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/vvkS5NztOE0/130614230415.htm
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paid in euro's into my uk business account avoid charges
I currently get paid in euros so I' ve got the linked accounts with caterallen. i.e. one sterling and one in euros. I think its 8E to recieve a euro payment.
BUT, even though its easy to transfer the rate is crap.
Instead, I use CurrencyFair. Basically, transfer the euros out into my CF account (costs me 29E - cheers Cater Allen). Then its like a peer-to-peer exchange rate thing as you convert to sterling.
Then its ?3 to transfer back to sterling cater allen.
Sounds like a potch but I get ?100s more a month sometimes. Also, I don't do a euro transfer every month so its not 29E every month.
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Draft NASA Funding Bill Cancels Asteroid Mission For Return To the Moon
First off, this nightmare that is ongoing with NASA, is NOT NASA's fault, but the fault, of the God Damn neo-cons that are running the house.
The majority of those shits are looking to keep NASA as a Job's bill. They do not care whether we go to the moon or not. THey want to spending our money on SLS which is mostly situated in neo-con districts( I note that a few dems back this as well, but they are pushing for both SLS and private space; spend, spend, spend).
So, what is insane about this? We will spend 20B for a launch vehicle that is mostly based on 60's/70's technology and design and will give us exactly ONE launch vehicle (though with several different designs). Since this vehicle will launch so infrequently, it will cost us 1.5-3B PER LAUNCH. Yes, it will cost as much or more than the shuttle did ( 1.5B per launch was the final price that we paid to send 7 ppl and 24.5 tonnes into LEO; that included the
The majority of those shits are looking to keep NASA as a Job's bill. They do not care whether we go to the moon or not. THey want to spending our money on SLS which is mostly situated in neo-con districts( I note that a few dems back this as well, but they are pushing for both SLS and private space; spend, spend, spend).
So, what is insane about this? We will spend 20B for a launch vehicle that is mostly based on 60's/70's technology and design and will give us exactly ONE launch vehicle (though with several different designs). Since this vehicle will launch so infrequently, it will cost us 1.5-3B PER LAUNCH. Yes, it will cost as much or more than the shuttle did ( 1.5B per launch was the final price that we paid to send 7 ppl and 24.5 tonnes into LEO; that included the
So, what is the sane Alternative? The one that Obama, dems, and even the tea-party is pushing: We need PRIVATE SPACE.
If we spend less than 2B over the next 2-3 years, we can have 3 launchers that will carry 7 ppl into leo (dragon rider/f9, atlas V with either cst-100 or dreamchaser). With this, we are guaranteed that we will NEVER lose cargo or human access to space again.
BUT, it gets better. Bigelow Aerospace has a SSA with NASA that both are working on getting private space to the moon BY 2020. It will costs less than the 20B that neo-cons are trying to force on NASA. Most importantly, by allowing NASA to pursue the asteroid AND help private space, we gain:
1) multiple launch vehicles so that we never lose space access again.
2) multiple tugs/fuel depots, that will include electric tugs (suitable for moving equipment/sats) and chemical tugs (suitable for moving ppl, or starting missions to extra solar).
3) multiple space stations at various altitudes in orbit, along with friendly nations helping to fund this.
4) a lunar base by 2020, again, with friendly nations helping to fund this (by paying the private companies money to put ppl on the surface).
5) Man on Mars by 2025.
6) learning on how to move asteroids around, and hopefully, prevent a large impact on earth. In addition, this technology will then allow private space to mine other asteroids.
And if we do this smart, we will then create a COTS-SHLV, in which we hold a contest for 2 launch systems to carry a minimum of 150 tonnes to LEO, for which we give 5B each to develop it. In addition, later one, we offer up 2 competitive contracts in which company will carry a minimum of 150 tonnes to LEO for no more than
You will note that the above spends just about the same as what the neo-cons want to spend on just building a rocket. BUT, if we do the above correctly, we will have NASA focus on just going to an asteroid, but also helping private space get BEO, and hopefully, NASA will be able to R&D new tech, such as nuke engines (we lead the world on this and our tech from the 60s is STILL ahead of what everybody else has).
With above approach, we convert NASA back into what it was before neo-cons turned them into a jobs program for themselves, get private space from being a cost center into a taxable item, and get ourselves BEO.
BUT, these god-for-saken neo-cons need to be stopped.
Source: http://rss.slashdot.org/~r/Slashdot/slashdotScience/~3/W2ROBMoa8_Y/story01.htm
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Saturday, June 15, 2013
Major hurdle cleared to diabetes transplants
June 13, 2013 ? Researchers at Washington University School of Medicine in St. Louis have identified a way to trigger reproduction in the laboratory of clusters of human cells that make insulin, potentially removing a significant obstacle to transplanting the cells as a treatment for patients with type 1 diabetes.
Efforts to make this treatment possible have been limited by a dearth of insulin-producing beta cells that can be removed from donors after death, and by the stubborn refusal of human beta cells to proliferate in the laboratory after harvesting.
The new technique uses a cell conditioning solution originally developed to trigger reproduction of cells from the lining of the intestine.
"Until now, there didn't seem to be a way to reliably make the limited supply of human beta cells proliferate in the laboratory and remain functional," said Michael McDaniel, PhD, professor of pathology and immunology. "We have not only found a technique to make the cells willing to multiply, we've done it in a way that preserves their ability to make insulin."
The findings are now available online in PLOS ONE.
The current method for harvesting human islets, which are comprised primarily of the insulin-producing beta cells, makes it necessary to find two or three donors to extract enough cells to produce an adequate supply of insulin to treat a single patient with diabetes.
The idea for the new technique came from an on-campus gathering to share research results. Lead author Haytham Aly, PhD, a postdoctoral research scholar, reported on his work with beta cells and was approached by Thaddeus Stappenbeck, MD, PhD, associate professor of pathology and immunology, who studies autoimmune problems in the gut. Stappenbeck had developed a medium that causes cells from the intestine's lining to proliferate in test tubes.
"He said, why don't you try it, and he gave us some samples," Aly said. "We put the solution in our freezer for a month or so, and when we finally gave it a try, we were amazed at the results: human beta cells in Dr. Stappenbeck's solution reproduced at a rate that was 20 times higher than beta cells in a solution that contained the sugar glucose."
The ability to produce large quantities of human beta cells in the laboratory gives the researchers hope that they could one day be transplanted into patients with type 1 diabetes.
The advantage of Stappenbeck's solution may be that it is designed to activate multiple growth signaling pathways in cells, according to the researchers. Earlier attempts to make beta cells proliferate focused on one or two growth pathways. The solution also activates genes that help prevent beta cells from dying.
Because pancreatic cancers are among the most deadly tumors, the scientists checked to make sure the proliferating beta cells weren't becoming more like cancer cells. They found that none of the factors known to contribute to pancreatic cancer were active in the laboratory-grown beta cells.
"This is an important concern to keep in mind if we are to expand human beta cells in culture with this medium and subsequently transplant them into patients," said Aly.
If the new availability of laboratory-grown beta cells makes it possible to treat patients with transplants from one donor instead of multiple donors, McDaniel noted, that might reduce the risk of immune system rejection of the transplants.
"Another benefit in using this novel growth medium to expand isolated human beta cells is that the cells remain healthier and have reduced levels of cell damage or death," Aly said. "That may also reduce the chances of immune system rejection."
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/YTo6Y6lwhkc/130613161833.htm
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Tuesday, June 11, 2013
Bolshoi won't renew star dancer's contract
MOSCOW (AP) ? The Bolshoi Theater won't renew the contract of Nikolai Tsiskaridze, a veteran principal dancer and teacher who for years has been in open conflict with managers at the celebrated Russian theater.
The dispute intensified after the Bolshoi ballet's artistic director was attacked in January by a man who threw acid in his face.
Bolshoi managers accused Tsiskaridze of inciting tensions within the theater that led to the attack, while Tsiskaridze portrayed the attack as the result of corruption and unfair treatment of dancers.
Bolshoi spokeswoman Katerina Novikova said Sunday that Tsiskaridze was told his contract won't be renewed when it expires at the end of June.
Tsiskaridze, who joined the Bolshoi in 1992, said in an NTV television interview that he questioned the theater's right to let him go.
Source: http://news.yahoo.com/bolshoi-wont-renew-star-dancers-contract-105627827.html
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Grant Hill supports wife Tamia at NYC concert
NEW YORK (AP) ? A week after he retired from the NBA, Grant Hill celebrated with his wife as she performed for a feverish crowd in New York City on Saturday night.
Hill and New York Knicks' Amar'e Stoudemire watched from the VIP section of the Highline Ballroom as Tamia (tah-MEE'-uh) sang R&B tunes for a few hundred people.
Hill last played for the Los Angeles Clippers. The 40-year-old also played for Detroit, Orlando and Phoenix in his 19-season career.
Tamia gave Hill a shout-out before singing the song "Still" saying, "We're celebrating almost 15 years of marriage."
Her fifth album, "Beautiful Surprise," was nominated for two Grammy Awards this year. She performed with ease Saturday, singing R&B jams like "Stranger In My House," ''Imagination," ''So Into You" and "Officially Missing You."
Source: http://news.yahoo.com/grant-hill-supports-wife-tamia-nyc-concert-154504783.html
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Monday, June 10, 2013
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